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BI-78D3

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SI-7865

BI-78D3, >98% (HPLC)

CAS No. : [883065-90-5]

IUPAC Name : 4-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-5-((5-nitrothiazol-2-yl)thio)-4H-1,2,4-triazol-3-ol

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Chemical Properites
Mol. Formula :
C13H9N5O5S2
Mol. Weight :
379.37
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BI‑78D3 is a selective, substrate‑competitive inhibitor of JNK that reduces JNK catalytic activity (IC50 = 280 nM). It is widely used as a tool compound for probing JNK‑dependent cellular stress responses.

References : Stebbins J. L et al.: Proc. Natl. Acad. Sci. U S A, 105(43), 16809-13, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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