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Bicalutamide EP impurity E

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SL-6765

Bicalutamide EP impurity E, >98%

CAS No. : [1080647-25-1]

IUPAC Name : (R)-N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-((R)-(4-fluorophenyl)sulfinyl)-2-hydroxy-2-methylpropanamide

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Chemical Properites
Mol. Formula :
C18H14F4N2O3S
Mol. Weight :
414.37
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Bicalutamide (Bicalutamide EP impurity E), which is an androgen receptor (AR) antagonist. It is primarily used to treat prostate cancer.

References : Clegg N. J. et al.: Cancer Res., 72(6),1494-1503, 2012; Colquhoun A. J. et al.: Prostate Cancer Prostatic Dis. 15(4), 346-52, 2012; Squillace R. M. et al.: Int. J. Oncol., 41(2), 425-32, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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