Binimetinib-13Cd3

SI-5522

Binimetinib-¹³Cd₃, >98% (HPLC)

Related CAS No. : [606143-89-9] of the unlabelled compound

Synonyms : ARRY-438162-¹³Cd₃; ARRY-162-¹³Cd₃; MEK162-¹³Cd₃

IUPAC Name : 5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-N-(2-hydroxyethoxy)-1-(methyl-¹³C-d₃)-1H-benzo[d]imidazole-6-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
Note: Binimetinib-13Cd3 is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!

Applications : Binimetinib-13C,d3 is a 13C- and deuterium labelled version analog of Binimetinib, which is an oral and selective MEK1/2 inhibitor developing for potential treatment of various cancers. Binimetinib inhibits MEK with an IC50 of 12 nM.

References : Serra V. et al.: J. Clin Invest., 123(6), 2551-2563, 2013; Kiessling M. K. et al.: Oncotarget., 6(39), 42183-96, 2015; Cheng H. et al.: Oncogene 35(23), 2961-70, 2016; Seip K. et al.: Oncotarget., 7(15), 19997-20015, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.