Binimetinib

SI-5248

Binimetinib, >98% (HPLC)

CAS No. : [606143-89-9]

MDL No. : MFCD22124525

Synonyms : ARRY-438162; ARRY-162; MEK162

IUPAC Name : 5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzo[d]imidazole-6-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
1G	Request A Quote		Back Order	Estimated to ship on 04 October 2026
5G	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Binimetinib is an oral and selective MEK1/2 inhibitor. Binimetinib inhibits MEK with an IC50 of 12 nM. Binimetinib has potential to treat various cancers.

References : Serra V. et al.: J. Clin Invest., 123(6), 2551-2563, 2013; Kiessling M. K. et al.: Oncotarget., 6(39), 42183-96, 2015; Cheng H. et al.: Oncogene 35(23), 2961-70, 2016; Seip K. et al.: Oncotarget., 7(15), 19997-20015, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.