Bisindolylmaleimide II-d3

SL-1233

Bisindolylmaleimide II-d₃, >98% (CP)

Isotopic Purity : 99 atom % D

Related CAS No. : [137592-45-1] of the unlabelled compound

IUPAC Name : 3-(1H-Indol-3-yl)-4-(1-(2-(1-methyl-d₃ pyrrolidin-2-yl)ethyl)-1H-indol-3-yl)-1H-pyrrole-2,5-dione

Price And Availability
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5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This is a deuterium labelled version of Bisindolylmaleimide II, which is a potent ATP-competitive protein kinase C (PKC) inhibitor. Also it inhibits PDK1 (IC50 = 14 μM), an important kinase in the insulin signaling pathway, and PKA (IC50 = 2.94 μM). This can be used as an internal reference standard.

References : Davis P. D. et al.: J. Med. Chem., 35, 177, 1992.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.