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BJJF-078

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SI-8165

BJJF-078, >98% (HPLC)

CAS No. : [2531244-56-9]

IUPAC Name : N-(5-((4-Acrylamidopiperidin-1-yl)sulfonyl)naphthalen-1-yl)-3,4-dimethoxybenzamide

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Chemical Properites
Mol. Formula :
C27H29N3O6S
Mol. Weight :
523.6
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BJJF-078 inhibits TG2 with low‑nanomolar potency in both human and mouse systems (IC50 = 41–54 nM) and also blocks TG1 at sub‑micromolar levels (IC50 = 0.16 µM). It is useful for probing TG2‑dependent pathways in multiple sclerosis research.

References : Chrobok N. L. et al.: PLoS One, 13(4), e0196433, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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