BMS-1

SI-6542

BMS-1, >98% (HPLC)

CAS No. : [1675201-83-8]

Synonyms : PD-1/PD-L1 inhibitor 1

IUPAC Name : (S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BMS‑1 inhibits the PD‑1/PD‑L1 interaction with nanomolar potency (IC₅₀ = 6–100 nM), enabling investigation of T‑cell activation and immune‑checkpoint signaling pathways relevant to cancer immunotherapy.

References : Zhao Y. et al.: Carcinogenesis, 2019; Li K. et al.: J. Drug Target, 27(3), 244-256, 2019; Zhang H. et al.: Vaccine, 37(15), 2090-2098, 2019;
Mengyuan Li. et al.: J. Immunother. Cancer, 8(2), e000293, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.