BMS-1001 hydrochloride

SI-6545

BMS-1001 hydrochloride, >98% (HPLC)

CAS No. : [2113650-04-5]

IUPAC Name : (2-((3-Cyanobenzyl)oxy)-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)-5-methylbenzyl)-D-serine hydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BMS‑1001 potently disrupts the human PD‑L1/PD‑1 interface (HTRF IC₅₀ = 2.25 nM) while maintaining low toxicity in cells. Its oral activity and high affinity make it a valuable tool for studying PD‑1/PD‑L1‑regulated immune‑checkpoint pathways.

References : Skalniak L. et al.: Oncotarget., 8(42), 72167-72181, 2017; Guzik K. et al.: J. Med. Chem., 60(13), 5857-5867, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.