BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride

SI-6549

BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride, >98% (HPLC)

CAS No. : [2691796-83-3]

IUPAC Name : 3-((4-Chloro-5-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)-2-((2-(piperazine-1-carbonyl)piperidin-1-yl)methyl)phenoxy)methyl)benzonitrile dihydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BMS‑1166‑N‑piperidine‑CO‑N‑piperazine·2HCl is a PROTAC‑ready BMS‑1166 derivative used to generate PD‑1/PD‑L1 degrader‑1 (IC₅₀= 39.2 nM), with the salt form offering better solubility and stability.

References : Cheng B. et al.: Eur. J. Med. Chem., 199, 112377, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.