BMS-200

SI-6543

BMS-200, >98% (HPLC)

CAS No. : [1675203-82-3]

IUPAC Name : (S)-4-((4-((3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)-2,5-difluorobenzyl)amino)-3-hydroxybutanoic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BMS‑200 inhibits the PD‑1/PD‑L1 protein–protein interaction with nanomolar potency (IC₅₀ = 80 nM) and induces PD‑L1 dimerization, thereby preventing PD‑1 binding and enabling investigation of T‑cell activation pathways relevant to cancer immunotherapy.

References : Katarzyna Guzik. et al.: J. Med. Chem., 60(13), 5857-5867, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.