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BMS-262084

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SI-7885

BMS-262084, >98% (HPLC)

CAS No. : [253174-92-4]

IUPAC Name : (2S,3R)-1-(4-(Tert-butylcarbamoyl)piperazine-1-carbonyl)-3-(3-guanidinopropyl)-4-oxoazetidine-2-carboxylic acid

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Chemical Properites
Mol. Formula :
C18H31N7O5
Mol. Weight :
425.49
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BMS‑262084 irreversibly inhibits factor XIa with low‑nanomolar potency (IC50= 2.8 nM) and also targets human tryptase (IC50 = 5 nM). Its biochemical profile underlies strong antithrombotic activity, supporting its use in mechanistic studies of coagulation pathways.

References : Schumacher W. A. et al.: Eur J. Pharmacol., 570(1-3), 167-74, 2007; Qian X. et al.: J. Org Chem., 67(11), 3595-600, 2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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