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SI-7192

BMS-3, >98% (HPLC)

CAS No. : [1338247-30-5]

IUPAC Name : N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)cyclopropanecarboxamide

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Chemical Properites
Mol. Formula :
C17H12Cl2F2N4OS
Mol. Weight :
429.27
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BMS‑3 selectively inhibits LIMK1 and LIMK2 with low‑nanomolar potency (IC50 = 5/6 nM), making it a valuable tool for studying LIMK‑mediated actin dynamics and related cellular processes.

References : Ross-Macdonald P. et al.: Mol. Cancer Ther., 7(11), 3490-8, 2008;
Romarowski A. et al.: Dev. Biol., 405(2), 237-49, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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