BMS-4

SI-7193

BMS-4, >98% (HPLC)

CAS No. : [905298-84-2]

Synonyms : LIMK1 inhibitor BMS-4

IUPAC Name : 1-Ethyl-3-(5-(6-(4-methoxy-2,6-dimethylphenyl)-2-(pyrazin-2-yl)pyrimidin-4-yl)thiazol-2-yl)urea

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BMS‑4 is a selective LIMK1/2 inhibitor that blocks cofilin phosphorylation, effectively modulating actin‑cytoskeleton dynamics. It shows strong biochemical activity yet is non‑cytotoxic in A549 cells, making it a useful tool compound for studying LIMK‑dependent signaling, cytoskeletal regulation, and cancer‑cell motility.

References : Collins R. et al.: J. Med. Chem., 65(20), 13705-13713, 2022. Ross-Macdonald P. et al.: Mol Cancer Ther., 7(11), 3490-8, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.