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BMS-4

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SI-7999

BMS-4, >98% (HPLC)

CAS No. : [905298-84-2]

Synonyms : LIMK1 inhibitor BMS-4

IUPAC Name : 1-Ethyl-3-(5-(6-(4-methoxy-2,6-dimethylphenyl)-2-(pyrazin-2-yl)pyrimidin-4-yl)thiazol-2-yl)urea

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Chemical Properites
Mol. Formula :
C23H23N7O2S
Mol. Weight :
461.54
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BMS‑4 inhibits LIMK1/2 and prevents phosphorylation of cofilin, leading to functional suppression of LIMK signaling. Notably, it does not induce cytotoxicity in A549 cells, supporting its use in mechanistic studies of LIMK‑regulated cytoskeletal processes.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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