BMS-8

SI-7332

BMS-8, >98% (HPLC)

CAS No. : [1675201-90-7]

IUPAC Name : 1-(3-Bromo-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BMS‑8 blocks PD‑1/PD‑L1 binding with an IC₅₀ of 7.2 µM and engages PD‑L1 to stabilize PD‑L1 homodimers. This dimerization prevents PD‑1 association and functionally inhibits checkpoint signaling.

References : Eun-Hye Kim et al.: Int. J. Mol Sci, 21(10), 3639, 2020; Danfeng Shi et al.: Front Chem., 7, 764, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.