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BMS-986104

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SI-6405

BMS-986104, >98% (HPLC)

CAS No. : [1622180-31-7]

IUPAC Name : ((1R,3S)-1-Amino-3-((R)-6-hexyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol

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Chemical Properites
Mol. Formula :
C22H35NO
Mol. Weight :
329.53
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BMS‑986104 selectively targets S1P1 and demonstrates strong in vivo efficacy in EAE models, matching the performance of FTY720. It also drives remyelination in LPC‑induced demyelination assays, highlighting its utility for studying S1P1‑mediated immune modulation and myelin repair.

References : Yang M. G. et al.: J. Med. Chem., 59(24), 11138-11147, 2016; Dhar T. G. et al.: ACS Med. Chem. Lett., 7(3), 283-288, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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