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BMS-986118

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SI-812

BMS-986118, >98% (HPLC)

CAS No. : [1610562-74-7]

IUPAC Name : 2-((4S,5S)-1-(4-(((3R)-1-(5-Chloro-2-methoxypyridin-4-yl)-3-methylpiperidin-4-yl)oxy)phenyl)-4-methyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-yl)acetic acid

Price And Availability
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5MGRequest A Quote
Back Order  Estimated to ship on 01 November 2026
25MGRequest A Quote
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100MGRequest A Quote
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250MGRequest A Quote
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500MGRequest A Quote
Back Order  Estimated to ship on 01 November 2026
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Note: BMS-986118 is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We will respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C25H28ClF3N4O4
Mol. Weight :
540.96
Appearance :
Solid
Melting Point :
185.5oC (lit)
For Laboratory research use only, not for drug, household or other uses.

Applications : BMS-986118 is a potent and selective GPR40 agonist with EC50 of 70 and 63 nM for hGPR40 and mGPR40, shows no PPARγ activity (EC50>47 uM).

References : Jun S. et al.: J. Med. Chem., 61(3), 681-694, 2018; Li Z. et al.: Expert Opin Investig Drugs 25(8), 871-890, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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