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BMS-986120

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SI-7111

BMS-986120, >98% (HPLC)

CAS No. : [1478712-37-6]

IUPAC Name : 4-(4-(((6-Methoxy-2-(2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl)benzofuran-4-yl)oxy)methyl)-5-methylthiazol-2-yl)morpholine

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Chemical Properites
Mol. Formula :
C23H23N5O5S2
Mol. Weight :
513.59
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BMS‑986120 is a first‑in‑class, orally active, reversible PAR4 antagonist with IC50 values of 9.5 nM in human blood and 2.1 nM in monkey blood. It exhibits potent and selective antiplatelet activity.

References : Wong P. C. et al.: Stroke, 47, A175, 2018; Wilson S. J. et al.: Arterioscler. Thromb. Vasc. Biol., 38(2), 448-456, 2018; Wong P. C. et al.: Sci. Transl. Med., 9(371), 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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