BMS-986122

SI-7629

BMS-986122, >98% (HPLC)

CAS No. : [313669-88-4]

IUPAC Name : 2-(3-Bromo-4-methoxyphenyl)-3-((4-chlorophenyl)sulfonyl)thiazolidine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BMS‑986122 selectively enhances μ‑opioid receptor signaling as a potent PAM, increasing β‑arrestin recruitment, G‑protein activation, and adenylyl cyclase inhibition in response to orthosteric agonists. It also potentiates DAMGO‑mediated [³⁵S]GTPγS binding in mouse brain membranes, highlighting its value for studying allosteric modulation of µ‑OR function.

References : Burford T. N. et al.: Proc. Natl. Acad. Sci. U S A., 110(26), 10830-10835, 2013; Kandasamy R. et al.: Proc. Natl. Acad. Sci. U S A., 118(16), e2000017118, 2021; Livingston K. E. et al.: Mol. Pharmacol., 93(2), 157-167, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.