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BMS-986141

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SI-7112

BMS-986141, >98% (HPLC)

CAS No. : [1478711-48-6]

IUPAC Name : 4-(4-(((6-Methoxy-2-(2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl)benzofuran-4-yl)oxy)methyl)thiazol-2-yl)-N,N-dimethylbenzamide

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Chemical Properites
Mol. Formula :
C27H23N5O5S2
Mol. Weight :
561.63
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BMS‑98614 is an orally bioavailable and highly selective antagonist of the thrombin receptor PAR‑4, demonstrating exceptional potency (IC50 = 0.4 nM). It produces strong antithrombotic effects, making it a valuable tool for studying PAR‑4–mediated platelet activation and thrombosis.

References : Scott Priestley E.et al.: J. Med. Chem., 65(13),8843-8854, 2022; Wong P. et al.: European Heart Journal, Volume 41, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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