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BMS-986158

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SI-6061

BMS-986158, >98% (HPLC)

CAS No. : [1800340-40-2]

IUPAC Name : (S)-2-(3-(1,4-Dimethyl-1H-1,2,3-triazol-5-yl)-5-(phenyl(tetrahydro-2H-pyran-4-yl)methyl)-5H-pyrido[3,2-b]indol-7-yl)propan-2-ol

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Chemical Properites
Mol. Formula :
C30H33N5O2
Mol. Weight :
495.63
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BMS-986158 is a potent BET inhibitor active in SCLC and TNBC cells (IC50 = 6.6–5 nM).

References : Yin M. et al.: Nat. Commun., 11(1), 1833, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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