BMS-986172

SI-7350

BMS-986172, >98% (HPLC)

CAS No. : [1808258-99-2]

IUPAC Name : (S)-4-(1-(Cyclopropylmethyl)-1H-pyrazol-3-yl)-6-(2-fluoro-4-(4,4,4-trifluorobutoxy)phenyl)-3-(5-oxo-4,5-dihydro-1H-tetrazol-1-yl)-6-(trifluoromethyl)-5,6-dihydropyridin-2(1H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BMS‑986172 is a potent, orally active, and selective MGAT2 inhibitor, showing IC₅₀ = 4.6 nM for human MGAT2 and 20 nM for mouse MGAT2. It effectively reduces food intake and body weight, making it a valuable tool compound for studying metabolic diseases, particularly obesity. Its strong MGAT2 selectivity and favorable pharmacological profile support its use in probing intestinal lipid absorption pathways and evaluating MGAT2‑targeted therapeutic strategies.

References : Meng W. et al.: J. Med. Chem., 66(18), 13135-13147, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.