BMS-986176

SI-7008

BMS-986176, >98% (HPLC)

CAS No. : [1815613-42-3]

Synonyms : LX-9211; AAK1-IN-1

IUPAC Name : (S)-1-((2',6-Bis(difluoromethyl)-[2,4'-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BMS‑986176 functions as a selective and brain‑penetrant AAK1 inhibitor with nanomolar potency (IC₅₀ = 2 nM). It is widely employed in neurodegenerative disease research to probe AAK1‑dependent pathways involved in neuronal function and pathology.

References : Guanglin L. et al.: J. Med. Chem., 65(6), 4457-4480, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.