BMS-986187

SI-7630

BMS-986187, >98% (HPLC)

CAS No. : [684238-37-7]

IUPAC Name : 3,3,6,6-Tetramethyl-9-(4-((2-methylbenzyl)oxy)phenyl)-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BMS‑986187 selectively enhances δ‑opioid receptor signaling as a potent PAM (EC₅₀ = 0.03 µM; pKb= 6.02), while lacking observable PAM activity at the μ‑opioid receptor. Its strong δ‑receptor preference makes it useful for dissecting subtype‑specific opioid signaling mechanisms.

References : Burford T. N. et al.: J. Med. Chem., 58(10), 4220-9, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.