BMS-986224

SI-6239

BMS-986224, >98% (HPLC)

CAS No. : [2055200-88-7]

IUPAC Name : 3-(5-((5-Chloropyridin-2-yl)methyl)-1,3,4-oxadiazol-2-yl)-5-(2,6-dimethoxyphenyl)-6-(ethoxymethyl)-4-hydroxypyridin-2(1H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BMS‑986224 is an oral APJ agonist with sub‑nanomolar affinity (K_d = 0.3 nM) and functional properties comparable to (Pyr¹)‑apelin‑13. Its pharmacological profile supports its use in probing APJ‑mediated cardioprotective signaling and heart‑failure biology.

References : Gargalovic P. et al.: Circ. Heart Fail, 14(3), e007351, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.