BMS-986313

SI-6205

BMS-986313, >98% (HPLC)

CAS No. : [2226319-10-2]

IUPAC Name : N-((3R,3aS,9bS)-9b-((4-Fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[a]naphthalen-3-yl)-2-hydroxy-2-methylpropanamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BMS‑986313 selectively inhibits RORγt with nanomolar potency (EC₅₀ = 3.6 nM) and reduces IL‑17 production in human whole blood (EC₅₀ = 50 nM). It is a valuable tool compound for probing RORγt‑dependent signaling and Th17‑driven inflammation.

References : Yang M. G. et al. : J. Med. Chem., 64(5), 2714-2724, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.