BMS-986318

SI-7101

BMS-986318, >98% (HPLC)

CAS No. : [2314378-09-9]

IUPAC Name : 6-(2-(5-Cyclopropyl-3-(3,5-dichloropyridin-4-yl)isoxazol-4-yl)-7-azaspiro[3.5]non-1-en-7-yl)-4-(trifluoromethyl)quinoline-2-carboxylic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BMS‑986318 is a potent non‑bile acid FXR agonist (EC₅₀ = 53–350 nM) with favorable ADME properties and efficacy in cholestasis/fibrosis models, useful for NASH research.

References : Joseph C. et al.: ACS Med. Chem. Lett., 12(9), 1413-1420, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.