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BMS-986339

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SI-7100

BMS-986339, >98% (HPLC)

CAS No. : [2477873-64-4]

IUPAC Name : (1s,3s)-N-((4-(5-(2-Fluoropropan-2-yl)-1,2,4-oxadiazol-3-yl)bicyclo[2.2.2]octan-1-yl)methyl)-3-hydroxy-N-(4'-(2-hydroxypropan-2-yl)-[1,1'-biphenyl]-3-yl)-3-(trifluoromethyl)cyclobutane-1-carboxamide

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Chemical Properites
Mol. Formula :
C35H41F4N304
Mol. Weight :
643.72
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BMS‑986339 is an orally active, potent FXR agonist that forms hydrogen bonds with His298 and Asn287. It is used in research on PBC, PSC, NASH, and anti‑fibrotic mechanisms.

References : Nara J. S. et al.: J. Med. Chem., 65(13), 8948-8960, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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