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BMT-090605 hydrochloride

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SI-7011

BMT-090605 hydrochloride, >98% (HPLC)

CAS No. : [2231664-45-0]

IUPAC Name : (S)-8-((2-Amino-4-methylpentyl)oxy)-4,6-dimethyl-5-oxo-5,6-dihydrobenzo[c][2,7]naphthyridine-9-carbonitrile hydrochloride

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Chemical Properites
Mol. Formula :
C21H24N4O2 • HCl
Mol. Weight :
400.91
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BMT‑090605 hydrochloride functions as a potent, selective AAK1 inhibitor with an IC50 of 0.6 nM and demonstrates robust antinociceptive activity. It also targets BIKE and GAK with IC50 values of 45 nM and 60 nM, respectively. These properties make it a valuable tool compound for probing kinase‑regulated mechanisms underlying neuropathic pain.

References : Kostich W. et al.: J. Pharmacol. Exp. Ther., 358(3), 371-86, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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