Bofutrelvir

SI-7448

Bofutrelvir, >98% (HPLC)

CAS No. : [2103278-86-8]

Synonyms : FB-2001

IUPAC Name : N-((S)-3-Cyclohexyl-1-oxo-1-(((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)amino)propan-2-yl)-1H-indole-2-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Bofutrelvir inhibits SARS‑CoV‑2 Mpro with an IC₅₀ of 53 nM and displays potent antiviral activity in cell‑based assays (EC₅₀ = 0.53 µM). It remains effective against several circulating variants, with EC₅₀ values ranging from 0.26 to 0.42 µM. When paired with Remdesivir, Bofutrelvir shows additive antiviral activity, highlighting its potential in combination regimens.

References : Ullrich S. et al.: Bioorg. Med. Chem Lett., 30(17), 127377, 2020; Shang W. et al.: Antiviral Res., 208, 105450,2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.