Bosentan

SL-2581

Bosentan, >98% (HPLC)

CAS No. : [147536-97-8]

MDL No. : MFCD00867375

Synonyms : Tracleer; Actelion; Ro 47-0203/039; Ro 47-0203

IUPAC Name : 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
50MG	90.00		Back Order	Estimated to ship on 04 October 2026
100MG	135.00		Back Order	Estimated to ship on 04 October 2026
250MG	255.00		Back Order	Estimated to ship on 04 October 2026
500MG	355.00		Back Order	Estimated to ship on 04 October 2026

Applications : Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ET_A and ET_B receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.

References : Dhillon S. et al.: Am J. Cardiovasc Drugs 9(5), 331-350, 2009; Akamata K. et al.: Arthritis Res Ther. 16(2), R86, 2014; Iglarz M. et al.: Life Sci. 118(2), 333-339, 2014; Son G. Y. et al.: PLoS One 11(12), e0167713, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.