Bosentan hydrate

SL-2582

Bosentan hydrate, >98% (HPLC)

CAS No. : [157212-55-0]

MDL No. : MFCD09751188

Synonyms : Benzenesulfonamide hydrate

IUPAC Name : 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide hydrate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
10MG	65.00		Back Order	Estimated to ship on 04 October 2026
25MG	85.00		Back Order	Estimated to ship on 04 October 2026
50MG	115.00		Back Order	Estimated to ship on 04 October 2026
100MG	195.00		Back Order	Estimated to ship on 04 October 2026
250MG	355.00		Back Order	Estimated to ship on 04 October 2026

Applications : Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ET_A and ET_B receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.

References : Dhillon S. et al.: Am J. Cardiovasc Drugs 9(5), 331-350, 2009; Akamata K. et al.: Arthritis Res Ther. 16(2), R86, 2014; Iglarz M. et al.: Life Sci. 118(2), 333-339, 2014; Son G. Y. et al.: PLoS One 11(12), e0167713, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.