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Bosentan USP related compound D

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Bosentan USP related compound D, >98%

CAS No. : [150728-13-5]

MDL No. : MFCD03839838

IUPAC Name : 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2’-bipyrimidine

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G20.00
In Stock  Estimated to ship on 20 September 2026
5G50.00
In Stock  Estimated to ship on 20 September 2026
10G70.00
In Stock  Estimated to ship on 20 September 2026
25G115.00
In Stock  Estimated to ship on 20 September 2026
100G455.00
In Stock  Estimated to ship on 20 September 2026
We accept
Chemical Properites
Mol. Formula :
C15H10Cl2N4O2
Mol. Weight :
349.17
Appearance :
Light brown solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of Bosentan, which is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors.

References : Dhillon S. et al.: Am J. Cardiovasc Drugs 9(5), 331-350, 2009; Akamata K. et al.: Arthritis Res Ther. 16(2), R86, 2014; Iglarz M. et al.: Life Sci. 118(2), 333-339, 2014; Son G. Y. et al.: PLoS One 11(12), e0167713, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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