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BPI-15086

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SI-7851

BPI-15086, >98% (HPLC)

CAS No. : [1644502-33-9]

IUPAC Name : N-(5-((5-Chloro-4-((2-(2-(dimethylamino)-2-oxoacetyl)phenyl)amino)pyrimidin-2-yl)amino)-4-methoxy-2-(4-methylpiperazin-1-yl)phenyl)acrylamide

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C29H33ClN8O4
Mol. Weight :
593.09
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BPI‑15086 is a potent, irreversible EGFR inhibitor that preferentially targets mutant EGFR variants, including the T790M resistance mutation. By suppressing mutant EGFR signaling, it serves as a valuable tool for investigating the biology and therapeutic targeting of NSCLC.

References : Wang S. et al.: Bioanalysis, 11(8), 773-784, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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