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BPN-14136

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SI-5036

BPN-14136, >98% (HPLC)

CAS No. : [1628945-93-6]

IUPAC Name : 2-((3aR,5r,6aS)-3a,6a-Dimethyl-5-(2-(trifluoromethyl)phenyl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-6-methylpyrimidine-4-carboxylic acid

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Back Order  Estimated to ship on 04 October 2026
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Note: BPN-14136is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C22H24F3N3O2
Mol. Weight :
419.45
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BPN-14136 is a potent retinol-binding protein 4 (RBP4) antagonist. BPN-14136 possesses exquisite in vitro RBP4 binding affinity and favorable drug-like characteristics and was found to reduce circulating plasma RBP4 levels in vivo in a robust manner (>90%).

References : Cioffi L. C et al.: J. Med. Chem., 58(15), 5863-5888, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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