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BQ-123-[13C6,15N]

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SL-1179

BQ-123-[13C6,15N], >98% (CP)

Isotopic Purity : 98 atom % 13C and 98 atom % 15N

Related CAS No. : [136553-81-6] of the unlabelled compound

Synonyms : Cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu-[13C6,15N]); Cyclo(Trp-Asp-Pro-Val-Leu-[13C6,15N])

IUPAC Name : Cyclo(D-alpha-aspartyl-L-prolyl-D-valyl-L-leucyl-[13C6, 15N]-D-tryptophyl)

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Chemical Properites
Mol. Formula :
C2513C6H42N515NO7
Mol. Weight :
617.65
Appearance :
Pale yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a labelled version of BQ-123, which is a highly potent, selective, and competitive ETA (endothelin) receptor antagonist (Ki = 40 nM for ETA versus Ki = 2.5 μM for ETB).

References : Nambi P. et al.: J. Pharmacol. Exp. Ther. 277, 1567,1996; Bax W. A. et al.: Trends Pharmacol. Sci. 15, 379, 1994; Ihara M. et al.: Biochem. Biophys. Res. Commun. 178, 132, 1991.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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