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BQ-123

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SL-1178

BQ-123, >98%

CAS No. : [136553-81-6]

Synonyms : Cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu); Cyclo(Trp-Asp-Pro-Val-Leu)

IUPAC Name : Cyclo(D-alpha-aspartyl-L-prolyl-D-valyl-L-leucyl-D-tryptophyl)

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Chemical Properites
Mol. Formula :
C31H42N6O7
Mol. Weight :
610.70
Appearance :
Pale yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BQ-123 is a highly potent, selective, and competitive ETA (endothelin) receptor antagonist (Ki = 40 nM for ETAversus Ki = 2.5 μM for ETB).

References : Nambi P. et al.: J. Pharmacol. Exp. Ther. 277, 1567,1996; Bax W. A. et al.: Trends Pharmacol. Sci. 15, 379, 1994; Ihara M. et al.: Biochem. Biophys. Res. Commun. 178, 132,1991.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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