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BRD-2879

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SI-5202

BRD-2879, >98% (HPLC)

CAS No. : [1304750-47-7]

Synonyms : BRD2879

IUPAC Name : 3-Cyclohexyl-1-(((2R,3R)-9-((3-fluorophenyl)ethynyl)-5-((S)-1-hydroxypropan-2-yl)-3-methyl-6,6-dioxido-2,3,4,5-tetrahydrobenzo[b][1,4]oxathiocin-2-yl)methyl)-1-methylurea

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5MGRequest A Quote
Back Order  Estimated to ship on 01 November 2026
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500MGRequest A Quote
Back Order  Estimated to ship on 01 November 2026
We accept
Note: BRD-2879is not in stock but can be available through custom synthesis. The estimated lead-time is 8-10 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C31H39FN2O5S
Mol. Weight :
570.72
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BRD-2879 is a potent and cell-active inhibitor of IDH1-R132H with a markedly different structure from previously reported probes with (IC50 = 50 nM for inhibiting IDH1-R132H enzyme). BRD-2879 represents a new structural class of mutant IDH1 inhibitors that, with optimization, may prove useful in the study of this enzyme and its role in cancer.

References : Law M. J. et al.: ACS Med. Chem. Lett., 7, 10, 944-949,2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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