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Brexpiprazole impurity 3 hydrochloride

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Brexpiprazole impurity 3 hydrochloride, >98%

CAS No. : [105684-41-1]

Synonyms : BRP-3

IUPAC Name : 1-(Benzo[b]thiophen-7-yl)piperazine hydrochloride

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25MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C12H14N2S . HCl
Mol. Weight :
254.78
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Brexpiprazole, which is a potent partial agonist at human 5-hydroxytryptamine (5-HT) 5-HT1A (Ki=0.12 nM) and dopamine D2L (Ki=0.3 nM) receptors, and an antagonist at 5-HT2A receptors (Ki=0.47 nM). Brexpiprazole is used to treat the symptoms of schizophrenia.

References : Ishima T. et al.: Eur. Neuropsychopharmacol., 25(4), 505-511, 2015; Yoshimi N. et al.: Eur. Neuropsychopharmacol., 25(3), 356-364, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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