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Brexpiprazole impurity B (BRX-B)

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SL-7370

Brexpiprazole impurity B (BRX-B), >98%

CAS No. : [2247155-42-4]

Synonyms : Brexpiprazole di-N-oxide

IUPAC Name : 1-(Benzo[b]thiophen-4-yl)-4-(4-((2-oxo-1,2-dihydroquinolin-7-yl)oxy)butyl)piperazine 1,4-dioxide

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Chemical Properites
Mol. Formula :
C25H27N3O4S
Mol. Weight :
465.57
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Brexpiprazole, which is a potent partial agonist at human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2L receptors, and an antagonist at 5-HT2A receptors. It is used to treat the symptoms of schizophrenia.

References : Ishima T. et al.: Eur. Neuropsychopharmacol., 25(4), 505-511, 2015; Yoshimi N. et al.: Eur. Neuropsychopharmacol., 25(3), 356-364, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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