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CAS No. : [649735-63-7]
Synonyms : (R)-Brivanib alaninate; BMS-582664
IUPAC Name : (S)-1-((4-((4-Fluoro-2-methyl-1H-indol-5-yl)oxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl)oxy)propan-2-yl D-alaninate
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C22H24FN5O4 | Mol. Weight : 441.46 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Brivanib alaninate selectively inhibits VEGFR2 with an IC50 of 25 nM and retains moderate inhibitory activity against VEGFR1 and FGFR1. Its kinase profile includes >240‑fold selectivity relative to PDGFRβ, supporting its use in angiogenesis‑related research.
References : Bhide R. S. et al.: J. Med. Chem., 49 (7), 2143-2146, 2006; Nakamura I. et al.: PLoS One., 10(11), e0142355, 2015; Huynh H. et al.: Clin. Cancer Res. 2008.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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