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Budesonide-d6 EP impurity F

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SL-5304

Budesonide-d6 EP impurity F, >98% (HPLC)

Isotopic Purity : 98 atom % D

Synonyms : 16α,17-[1-Methylethylidenebis(oxy)]-11β,21-dihydroxypregna-1,4-diene-3,20-dione-d6; Desonide-d6

IUPAC Name : (6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-Hydroxy-8b-(2-hydroxyacetyl)-6a,8a-dimethyl-10,10-bis(methyl-d3)-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one

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Chemical Properites
Mol. Formula :
C24H26D6O6
Mol. Weight :
422.55
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version an impurity of Budesonide (Budesonide-d3 EP impurity F), which is a glucocorticoid steroid for the treatment of asthma, non-infectious rhinitis.

References : Stellato C. et al.: J. Immunol., 163(10), 5624-5632, 1999; Bandi N. et al.: Eur J. Pharmacol., 425(2), 109-116, 2001; Ek A. et al.: Allergy 54(7), 691-699, 1999; Jansson A. H. et al.: Vascul Pharmacol., 43(2), 101-111, 2005; Yao R. et al.: Oncogene 23(46), 7746-7752, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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