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Budesonide EP impurity I

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SL-5308

Budesonide EP impurity I, >98%

CAS No. : [113930-13-5]

Synonyms : 11β,17,21-Trihydroxy-3,20-dioxopregna-1,4-dien-16α-yl butanoate; 16α-Butyloxyprednisolone

IUPAC Name : (8S,9S,10R,11S,13S,14S,16R,17S)-11,17-Dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-16-yl butyrate

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Chemical Properites
Mol. Formula :
C25H34O7
Mol. Weight :
446.54
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Budesonide (Budesonide EP impurity I), which is a glucocorticoid steroid for the treatment of asthma, non-infectious rhinitis.

References : Stellato C. et al.: J. Immunol., 163(10), 5624-5632, 1999; Bandi N. et al.: Eur J. Pharmacol., 425(2), 109-116, 2001; Ek A. et al.: Allergy 54(7), 691-699, 1999; Jansson A. H. et al.: Vascul Pharmacol., 43(2), 101-111, 2005; Yao R. et al.: Oncogene 23(46), 7746-7752, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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