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CAS No. : [944396-07-0]
MDL No. : MFCD18251596
Synonyms : NVP-BKM120; BKM120
IUPAC Name : 5-(2,6-Dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | 65.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | 95.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | 145.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | 215.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | 355.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | 525.00 | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C18H21F3N6O2 | Mol. Weight : 410.39 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : NVP-BKM120 is a pan-class I PI3K inhibitor, with IC50s of 52, 166, 116 and 262 nM for p110α, p110β, p110δ and p110γ, respectively.
References : Maira S. M. et al.: Mol. Cancer Ther.,11(2), 317-328, 2012; Pei Y. et al.: Cancer Cell 21(2), 155-167, 2012; Koul D. et al.: Clin Cancer Res.,18(1), 184-195, 2012.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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