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SI-1784

Buparlisib, 98% (HPLC)

CAS No. : [944396-07-0]

MDL No. : MFCD18251596

Synonyms : NVP-BKM120; BKM120

IUPAC Name : 5-(2,6-Dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MG65.00
Back Order  Estimated to ship on 04 October 2026
10MG95.00
Back Order  Estimated to ship on 04 October 2026
50MG145.00
Back Order  Estimated to ship on 04 October 2026
100MG215.00
Back Order  Estimated to ship on 04 October 2026
250MG355.00
Back Order  Estimated to ship on 04 October 2026
500MG525.00
Back Order  Estimated to ship on 04 October 2026
We accept
Chemical Properites
Mol. Formula :
C18H21F3N6O2
Mol. Weight :
410.39
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : NVP-BKM120 is a pan-class I PI3K inhibitor, with IC50s of 52, 166, 116 and 262 nM for p110α, p110β, p110δ and p110γ, respectively.

References : Maira S. M. et al.: Mol. Cancer Ther.,11(2), 317-328, 2012; Pei Y. et al.: Cancer Cell 21(2), 155-167, 2012; Koul D. et al.: Clin Cancer Res.,18(1), 184-195, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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