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BVT-948

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SI-6654

BVT-948, >98% (HPLC)

CAS No. : [39674-97-0]

IUPAC Name : 4-Hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione

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Chemical Properites
Mol. Formula :
C14H11NO3
Mol. Weight :
241.25
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BVT-948 inhibits protein tyrosine phosphatases and displays off‑target activity toward multiple P450 isoforms as well as the lysine methyltransferase SETD8 (KMT5A), making it a versatile tool for probing intersecting signaling and epigenetic pathways.

References : Liljebris C. et al.: J. Pharmacol. Exp. Ther., 309(2), 711-9, 2004; Blum G. et al.: ACS. Chem. Biol., 9(11), 2471-8, 2014; Hwang B. M. et al.: B. M. B. Rep., 46(11), 533-8, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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