C-1889

SI-6710

C-1889, >98% (HPLC)

CAS No. : [432001-19-9]

Synonyms : TTI-101

IUPAC Name : N-(1',2-Dihydroxy-[1,2'-binaphthalen]-4'-yl)-4-methoxybenzenesulfonamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : C188‑9 is a potent STAT3 SH2‑domain inhibitor (Kd = 4.7 nM) that blocks STAT3 activation, modulates STAT1 signaling, enhances DAC‑induced demethylation, suppresses tumor growth, and prevents cancer‑associated muscle atrophy.

References : Bharadwaj U. et al.: Oncotarget., 7(18), 26307-26330, 2016; Kong R. et al.: Front. Oncol., 10, 612, 2020; Ono Y. et al.: Sci. Rep., 16(1), 5008, 2026; Lewis K. M. et al.: Lung Cancer., 90(2), 182-90, 2015; Redell M.S. et al.: Blood., 117(21), 5701-5709, 2011; Silva K. A. et al.: J. Biol. Chem. 290(17), 11177-11187, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.