Cabozantinib-d4

SL-7383

Cabozantinib-d₄, >98%

Isotopic Purity : 98 atom % D

CAS No. : [1802168-53-1]

IUPAC Name : N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl-2,3,5,6-d₄)cyclopropane-1,1-dicarboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Cabozantinib-d₄ is a deuterium labelled version an analog of Cabozantinib, which is an inhibitor of the tyrosine kinases c-Met and VEGFR2, and also inhibits AXL and RET. It is used to treat medullary thyroid cancer, renal cell carcinoma, and hepatocellular carcinoma.

References : You W. K. et al.: Cancer Res., 71(14), 4758-4768, 2011; Torres K. E. et al.: Clin Cancer Res., 17(12), 3943-3955, 2011; Yakes F. M. et al.: Mol Cancer Ther., 10(12), 2298-2308, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.