Cabozantinib (S)-malate

SI-4525

Cabozantinib (S)-malate, >98% (HPLC)

CAS No. : [1140909-48-3]

MDL No. : MFCD20923480

Synonyms : BMS-907351 malate; XL184 malate

IUPAC Name : N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (S)-2-hydroxysuccinate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	30.00		Back Order	Estimated to ship on 04 October 2026
5G	95.00		Back Order	Estimated to ship on 04 October 2026
25G	365.00		Back Order	Estimated to ship on 04 October 2026

Applications : Cabozantinib is an inhibitor of the tyrosine kinases c-Met and VEGFR2, and also inhibits AXL and RET. It is used to treat medullary thyroid cancer, renal cell carcinoma, and hepatocellular carcinoma.

References : You W. K. et al.: Cancer Res., 71(14), 4758-4768, 2011; Torres K. E. et al.: Clin Cancer Res., 17(12), 3943-3955, 2011; Yakes F. M. et al.: Mol Cancer Ther., 10(12), 2298-2308, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.