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Calcitriol

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SL-5644

Calcitriol, >98%

CAS No. : [32222-06-3]

Synonyms : RO215535; Topitriol

IUPAC Name : (1R,3S,Z)-5-(2-((1R,3aS,7aR,E)-1-((R)-6-Hydroxy-6-methylheptan-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol

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Chemical Properites
Mol. Formula :
C27H44O3
Mol. Weight :
416.65
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Calcitriol is a metabolite of Vitamin D3, which is a form of vitamin D. It binds and activates a H305F/H397Y mutant vitamin D receptor (VDR). Vitamin D is a fat-soluble vitamin that helps body absorb calcium and phosphorus.

References : Ousley A. M. et al.: J. Steroid Biochem Mol Biol., 125(3-5), 202-210, 2011; Hector D. et al.: Archives of Biochemistry and Biophysics 505(2), 226-230, 2011; Diesing D. et al.: Anticancer Res., 26(4A), 2755-2759, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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