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Calcitriol-d6

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Calcitriol-d6, >98%

CAS No. : [78782-99-7]

Synonyms : RO215535-d6; Topitriol-d6

IUPAC Name : (1R,3S,Z)-5-(2-((1R,3aS,7aR,E)-1-((R)-6-Hydroxy-6-(methyl-d3)heptan-2-yl-7,7,7-d3)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C27H38D6O3
Mol. Weight :
422.68
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Calcitriol-d6 is a deuterium labelled version metabolite of Vitamin D3, which is a form of vitamin D. It binds and activates a H305F/H397Y mutant vitamin D receptor (VDR). Vitamin D is a fat-soluble vitamin that helps body absorb calcium and phosphorus.

References : Ousley A. M. et al.: J. Steroid Biochem Mol Biol., 125(3-5), 202-210, 2011; Hector D. et al.: Archives of Biochemistry and Biophysics 505(2), 226-230, 2011; Diesing D. et al.: Anticancer Res., 26(4A), 2755-2759, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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